Lalistat 1 ( ZINC795230 )

产品货号. M28175 CAS No. 501104-16-1

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Lalistat 1
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Lalistat 1 is an inhibitor of lysosomal acid lipase (LAL, IC50 = 68 nM) and IgA1 protease for H. influenzae.
产品描述

Lalistat 1 is an inhibitor of lysosomal acid lipase (LAL, IC50 = 68 nM) and IgA1 protease for H. influenzae. Lalistat 1 can be used in studies about niemann-pick type C diseases.(In Vitro):Lalistat 1 (0-100 μM) dose-dependently inhibits IgA1P B1 and B2, almost completely at 50 μM and completely at 100 μM .Lalistat 1 reduces cholesterol accumulation in lysosome-like reservoirs of GM03123 human fibroblasts lacking NPC1 .
同义词

ZINC795230
通路

GPCR/G Protein
靶点

Antibacterial
受体

MMP-12
研究领域

——
适应症

——

1.Morales R, et al. Crystal structures of novel non-peptidic, non-zinc chelating inhibitors bound to MMP-12. J Mol Biol. 2004 Aug 20;341(4):1063-76.

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